发明名称 |
Structure enclosing hematopoietic progenitor cells from ES cells and method for preparing blood cells using the same |
摘要 |
An object of the present invention is to provide a sac-like structure enclosing hematopoietic progenitor cells and a method for preparing the sac-like structure as well as a method for efficiently preparing blood cells such as mature megakaryocytes and platelets from the sac-like structure. The present invention provides a sac-like structure enclosing hematopoietic progenitor cells, the sac-like structure being obtained by plating ES cells onto feeder cells and culturing the ES cells under suitable conditions for inducing hematopoietic progenitor cell differentiation. Moreover, the present invention provides a method for producing various blood cells, the method comprising further culturing hematopoietic progenitor cells enclosed in the sac-like structure under suitable conditions for inducing blood cell differentiation. |
申请公布号 |
GB2455472(B) |
申请公布日期 |
2011.07.20 |
申请号 |
GB20090006137 |
申请日期 |
2007.10.04 |
申请人 |
THE UNIVERSITY OF TOKYO |
发明人 |
HIROMITSU NAKAUCHI;KOJI ETO;NAOYA TAKAYAMA;HIDEKAZU NISHIKI-I;HIROKO TSUKUI |
分类号 |
C12N5/0789;A61K35/14;C12N5/078 |
主分类号 |
C12N5/0789 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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