发明名称 Substituted benzyl ester derivative and use thereof
摘要 The present invention relates to a pharmaceutical composition, a food composition or a cosmetic composition, containing one or more kinds of a compound represented by the following formula (I′) wherein R1 is a hydrogen atom, a hydroxyl group, a methoxy group or an ethoxy group, R2 is a hydroxyl group, a methoxy group or an acetoxy group, or R1 and R2 in combination optionally form a methylenedioxy group, R is represented by the following formula wherein Y is an ethylene group or a vinylene group, m and n are each an integer of 0 to 7, which satisfy m+n=2 to 8, and R3 and R4 are each independently a hydrogen atom, a methyl group or an ethyl group, provided that, (1) when R1 is a methoxy group, then R2 is not a hydroxyl group; and (2) when R1 is a hydroxyl group, then R2 is not a hydroxyl group and an acetoxy group. According to the present invention, a stable capsinoid derivative is provided, and a pharmaceutical composition, a food composition, a cosmetic composition and the like containing the derivative as an active ingredient can be provided.
申请公布号 US7981460(B2) 申请公布日期 2011.07.19
申请号 US20080345249 申请日期 2008.12.29
申请人 AJINOMOTO CO., INC. 发明人 AMINO YUSUKE;TAKINO YOSHINOBU
分类号 A61K31/235;A23L1/30;C07D317/44;C07D323/02 主分类号 A61K31/235
代理机构 代理人
主权项
地址