| 发明名称 |
BRITTLE-COATING, SOFT CORE DOSAGE FORM |
| 摘要 |
The present invention provides an oral dosage form for delivering active agents having a soft core with an active agent particles, which have an average size of greater than about 50 µm, and a brittle shell encasing the soft core, wherein the weight ratio of drug particles to shell being from about 1:0:0.5 to about 1.0:15.
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| 申请公布号 |
CA2391439(C) |
申请公布日期 |
2011.07.19 |
| 申请号 |
CA20022391439 |
申请日期 |
2002.06.25 |
| 申请人 |
MCNEIL-PPC, INC. |
发明人 |
BUNICK, FRANK J.;BURKE, JOHN J.;GILMOR, TIMOTHY P.;PAPALINI, MICHELLE |
| 分类号 |
A61J3/07;A61K9/28;A61K9/00;A61K9/14;A61K9/20;A61K9/34;A61K9/36;A61K31/135;A61K31/137;A61K31/167;A61K31/192;A61K31/4402;A61K31/485 |
主分类号 |
A61J3/07 |
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