发明名称 |
Addition salts of angiotensin-converting enzyme inhibitors with no donor acids, a process for their preparation and pharmaceutical compositions containing them |
摘要 |
Compounds of formula (I): (A)m·(B)n  (I) wherein A represents an angiotensin-converting enzyme inhibitor compound containing at least one salt-forming basic function, B represents a compound containing at least one salt-forming acid function and at least one NO donor group, m represents the number of acid functions of B that have been converted to a salt and n represents the number of basic functions of A that have been converted to a salt, the bond or bonds between A and B being of the ionic type. Medicinal products containing the same which are useful in treating cardiovascular pathologies.
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申请公布号 |
US7981920(B2) |
申请公布日期 |
2011.07.19 |
申请号 |
US20080283928 |
申请日期 |
2008.09.17 |
申请人 |
LES LABORATOIRES SERVIER |
发明人 |
DE NANTEUIL GUILLAUME;PORTEVIN BERNARD;GLOANEC PHILIPPE;PARMENTIER JEAN-GILLES;BENOIST ALAIN;VERBEUREN TONY;RUPIN ALAIN;COURCHAY CHRISTINE;SIMONET SERGE |
分类号 |
A61K31/404;C07D209/12 |
主分类号 |
A61K31/404 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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