发明名称 α-form orβ-form crystal of acetanilide derivative
摘要 To provide novel crystals useful as an ingredient for the production of a diabetes remedy. The invention is concerned with α-form crystal and &bgr;-form crystal of (R)-2-(2-aminothiazol-4-yl)-4′-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetanilide. The α-form crystal does not exhibit hygroscopicity and has stability such that it can be used as a medicine, and is useful for mass synthesis in the industrial production. The &bgr;-form crystal does not relatively exhibit hygroscopicity and is also useful as a production intermediate of the α-form crystal.
申请公布号 US7982049(B2) 申请公布日期 2011.07.19
申请号 US20080007653 申请日期 2008.01.14
申请人 ASTELLAS PHARMA INC. 发明人 KAWAZOE SOUICHIROU;SAKAMOTO KENICHIROU;AWAMURA YUJI;MARUYAMA TATSUYA;SUZUKI TAKAYUKI;ONDA KENICHI;TAKASU TOSHIYUKI
分类号 A61K31/426;A61P3/10;C07D277/40;C07D277/44 主分类号 A61K31/426
代理机构 代理人
主权项
地址