发明名称 |
α-form orβ-form crystal of acetanilide derivative |
摘要 |
To provide novel crystals useful as an ingredient for the production of a diabetes remedy. The invention is concerned with α-form crystal and &bgr;-form crystal of (R)-2-(2-aminothiazol-4-yl)-4′-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetanilide. The α-form crystal does not exhibit hygroscopicity and has stability such that it can be used as a medicine, and is useful for mass synthesis in the industrial production. The &bgr;-form crystal does not relatively exhibit hygroscopicity and is also useful as a production intermediate of the α-form crystal.
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申请公布号 |
US7982049(B2) |
申请公布日期 |
2011.07.19 |
申请号 |
US20080007653 |
申请日期 |
2008.01.14 |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
KAWAZOE SOUICHIROU;SAKAMOTO KENICHIROU;AWAMURA YUJI;MARUYAMA TATSUYA;SUZUKI TAKAYUKI;ONDA KENICHI;TAKASU TOSHIYUKI |
分类号 |
A61K31/426;A61P3/10;C07D277/40;C07D277/44 |
主分类号 |
A61K31/426 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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