发明名称 METHOD AND COMPOSITIONS EMPLOYING FORMULATIONS OF LECITHIN OILS AND NSAIDS FOR PROTECTING THE GASTROINTESTINAL TRACT AND PROVIDING ENHANCED THERAPEUTIC ACTIVITY
摘要 A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulstion for internal, oral, direct or topical administration.
申请公布号 CA2431606(C) 申请公布日期 2011.07.19
申请号 CA20012431606 申请日期 2001.12.19
申请人 THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 发明人 LICHTENBERGER, LENARD
分类号 A61K47/24;A61K9/06;A61K9/08;A61K9/10;A61K9/107;A61K9/127;A61K31/167;A61K31/19;A61K31/192;A61K31/405;A61K31/60;A61K31/616;A61K31/66;A61K45/00;A61K47/44;A61K47/48;A61P1/02;A61P1/04;A61P9/00;A61P17/02;A61P25/28;A61P27/02;A61P27/04;A61P29/00;A61P35/00;A61P43/00 主分类号 A61K47/24
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