发明名称 |
Pharmaceutical compositions and methods for delivering nucleic acids into cells |
摘要 |
The present invention relates to methods of delivering nucleic acids into cells using a nucleic acid binding molecule containing a multimeric or spacer-incorporated protein transduction domain (PTD). The invention also relates to novel compositions that contain a nucleic acid complexed or conjugated with a nucleic acid binding molecule. The nucleic acid binding molecule may contain a multimeric or spacer-incorporated PTD, and may further contain a nucleic acid binding region. The nucleic acid complexes or conjugations of the present invention may be employed to inhibit expression of a target gene, and/or determine the function of a target gene.
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申请公布号 |
US7981446(B2) |
申请公布日期 |
2011.07.19 |
申请号 |
US20080277000 |
申请日期 |
2008.11.24 |
申请人 |
FORHUMANTECH. CO., LTD. |
发明人 |
LEE SANG-KYOU;LEE SEUNG-KYOU;CHOI KI-DOO |
分类号 |
A61K9/16;A61K35/16;A61K48/00;C12N15/87 |
主分类号 |
A61K9/16 |
代理机构 |
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地址 |
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