KDR-specifikke humane antistoffer og anvendelser deraf

摘要

The application provides antibodies that bind to KDR with an affinity comparable to or higher than human VEGF, and that neutralize activation of KDR. Antibodies include whole immunoglobulins, monovalent Fabs and single chain antibodies, multivalent single chain antibodies, diabodies, triabodies, and single domain antibodies. The application further provides nucleic acids and host cells that encode and express these antibodies.