| 发明名称 |
FGFR agonister |
| 摘要 |
The present invention relates to the use of Fibroblast-Growth Factor Receptor (FGFR) agonists for the diagnosis, prevention and/or treatment of pathological conditions including, but not limited to hyperproliferative disorders, bone diseases and vascular diseases. Particularly, the use of FGFR-4 agonists, e.g. anti-FGFR-4 antibodies is described. Further, the invention relates to a pharmaceutical composition comprising the agonist as described above and a screening procedure. |
| 申请公布号 |
DK1469878(T3) |
申请公布日期 |
2011.07.18 |
| 申请号 |
DK20030702574T |
申请日期 |
2003.01.30 |
| 申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. |
发明人 |
BANGE, JOHANNES;ULLRICH, AXEL |
| 分类号 |
A61K38/18;G01N33/50;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P5/14;A61P9/00;A61P9/10;A61P11/06;A61P15/00;A61P19/00;A61P19/08;A61P19/10;A61P35/00;A61P35/02;A61P43/00;C07K14/71;C07K16/18;C07K16/28;C12N5/10;C12N5/20;C12N15/09;C12Q1/02;G01N33/15 |
主分类号 |
A61K38/18 |
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