ENZYMATIC MODIFICATION IN A CONTINUOUSLY REGENERATED PACKED BED COLUMN

摘要

16 - ENZYMATIC MODIFICATION IN A CONTINUOUSLY REGENERATED PACKED BED COLUMN ABSTRACT A PROCESS FOR THE MODIFICATION OF A SUBSTRATE COMPRISING PASSING THE SUBSTRATE 5 THROUGH A PACKED BED COLUMN OF A SPECIFIC VOLUME OF IMMOBILIZED ENZYME WHEREIN THE SUB'STRATE ENTERS THE COLUMN AT OR NEAR ONE END OF THE COLUMN (THE 'INLET END') AND THE MODIFIED SUBSTRATE EXITS AT OR NEAR THE OPPOSITE END OF THE COLUMN (THE 'OUTLET END'), A PORTION OF THE VOLUME OF IMMOBILIZED ENZYME IS PERIODICALLY REMOVED AT OR NEAR TO THE INLET END OF THE COLUMN, AND AN 10 EQUIVALENT PORTION OF IMMOBILIZED ENZYME IS PERIODICALLY ADDED AT OR NEAR TO THE OUTLET END OF THE COLUMN.