EGFR AND PAR2 REGULATION OF INTESTINAL PERMEABILITY
摘要
<p>The present invention provides a method of treating an autoimmune disease, comprising the steps of increasing transepithelial electrical resistance leading to decreased cell permeability. Further provided is ajnethod of treating celiac disease in an individual in need of such treatment, comprising the steps of: administering an antibody directed against single chain zonulin thereby inhibiting epidermal growth factor receptor and inhibiting PAR2.</p>
申请公布号
WO2010144140(A4)
申请公布日期
2011.07.14
申请号
WO2010US01670
申请日期
2010.06.10
申请人
UNIVERSITY OF MARYLAND, BALTIMORE;FASANO, ALESSIO;LAMMERS, KAREN;SHEA-DONOHUE, TEREZ;GOLDBLUM, SIMEON