COMPOSITIONS AND METHODS FOR TREATING GLIOBLASTOMA GBM
摘要
Methods of treating a malignant glioma in a subject are disclosed. The methods comprise administering to the subject a therapeutically effective amount of a viral vector comprising: (i) a first polynucleotide sequence encoding a Fas-chimera (Fas-c), said first polynucleotide sequence comprising SEQ ID NOs: 2 and 3; and (ii) a second polynucleotide sequence encoding an endothelial cell-specific promoter or a periendothelial cell-specific promoter.
申请公布号
WO2011083466(A1)
申请公布日期
2011.07.14
申请号
WO2011IL00009
申请日期
2011.01.05
申请人
VASCULAR BIOGENICS LTD.;COHEN, YAEL;BANGIO, LIVNAT;BRENNER, ANDREW J.;BREITBART, EYAL
发明人
COHEN, YAEL;BANGIO, LIVNAT;BRENNER, ANDREW J.;BREITBART, EYAL