| 发明名称 |
COMPOSITIONS AND METHODS FOR INCREASING SERUM HALF-LIFE |
| 摘要 |
Provided herein are glycovariant Fc fusion proteins having increased serum half lives. Also provided are methods for increasing the serum half life of an Fc fusion protein by introducing one or more non-endogenous glycosylation sites. |
| 申请公布号 |
US2011171218(A1) |
申请公布日期 |
2011.07.14 |
| 申请号 |
US20100959220 |
申请日期 |
2010.12.02 |
| 申请人 |
ACCELERON PHARMA INC. |
发明人 |
SEEHRA JASBIR;KNOPF JOHN;KUMAR RAVINDRA |
| 分类号 |
A61K39/395;A61P25/16;A61P25/28;A61P29/00;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P33/00;A61P37/06;C07H21/00;C07K19/00;C12N1/00;C12N5/10;C12P21/00 |
主分类号 |
A61K39/395 |
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