发明名称 |
RECOMBINANT BUTYRYLCHOLINESTERASES AND TRUNCATES THEREOF |
摘要 |
<p>Isolated nucleic acids encoding polypeptides that exhibit butyrylcholinesterase (BChE) enzyme activity are disclosed, along with molecular criteria for preparing such nucleic acids, including codon optimization. Methods of preparing modified and/or truncated BChE molecules having selected properties, especially selective formation of monomers, are also described. Vectors and cells containing and/or expressing the nucleic acids are also disclosed.</p> |
申请公布号 |
CA2784861(A1) |
申请公布日期 |
2011.07.14 |
申请号 |
CA20102784861 |
申请日期 |
2010.12.21 |
申请人 |
PHARMATHENE, INC. |
发明人 |
YIM, KALVIN;DANSO, STEVEN;HAUSKNECHT, EDWARD |
分类号 |
C12N15/55;C12N9/16;C12N15/85 |
主分类号 |
C12N15/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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