发明名称 |
FIBRINOGEN PREPARATIONS ENRICHED IN FIBRINOGEN WITH AN EXTENDED ALPHA CHAIN. |
摘要 |
The present invention relates to fibrinogen preparations enriched in a-extended fibrinogen. Compositions comprising such preparations show improved clotting properties compared to preparations based on HMW Fib which typically contain no or only low amounts of a-extended fibrinogen. In particular, clot formation time and the clot strength of a clot made by a-extended fibrinogen are improved. In addition, plasmin-mediated degradation of a-extended fibrinogen is reduced as compared to plasma derived fibrinogen. |
申请公布号 |
CA2785594(A1) |
申请公布日期 |
2011.07.14 |
申请号 |
CA20112785594 |
申请日期 |
2011.01.07 |
申请人 |
PROFIBRIX BV |
发明人 |
GRIMBERGEN, JOSEPH;KOOPMAN, JACOB;BOUT, ABRAHAM |
分类号 |
A61K38/36 |
主分类号 |
A61K38/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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