Polar silanes for binding to substrates and use of the bound substrates in chromatography

摘要

Polyfunctional silicon compounds having one of the following structures: wherein at least one of R,R and R is a leaving group which, after leaving, permits the Si in one of said structures to form a Si-O-Si or Si-O-Zr bond, wherein L, L and L comprise alkyl or substituted alkyl chains from 1 to 100 in length, wherein m = 1-100; wherein N - PG, N - PG and N - PG are nitrogen-containing polar groups; wherein each of E, E, and E comprise alkyl, substituted alkyl, aryl, or substituted aryl groups, comprising 1-50 carbon atoms, and exclude functional groups selected from the group consisting of hydroxyl, carboxyl, amino, thio, halo and sulfonate moieties. Also, such compounds bound to substrates for use as chromatography.packing.