发明名称 |
COMPOSITIONS AND METHODS FOR TREATING GLIOBLASTOMA GBM |
摘要 |
Methods of treating a malignant glioma in a subject are disclosed. The methods comprise administering to the subject a therapeutically effective amount of a viral vector comprising: (i) a first polynucleotide sequence encoding a Fas-chimera (Fas-c), said first polynucleotide sequence comprising SEQ ID NOs: 2 and 3; and (ii) a second polynucleotide sequence encoding an endothelial cell-specific promoter or a periendothelial cell-specific promoter.
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申请公布号 |
CA2786377(A1) |
申请公布日期 |
2011.07.14 |
申请号 |
CA20112786377 |
申请日期 |
2011.01.05 |
申请人 |
VASCULAR BIOGENICS LTD. |
发明人 |
COHEN, YAEL;BANGIO, LIVNAT;BRENNER, ANDREW J.;BREITBART, EYAL |
分类号 |
C12N15/00;C07K14/705;C12N15/113;C12N15/62;C12N15/86;C12N15/861 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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