摘要 |
PROBLEM TO BE SOLVED: To provide a 4-hydroxytetrahydropyran derivative (general formula (6)) of a synthetic intermediate of a compound having a tetrahydropyran skeleton and useful as a liquid crystal composition, and to provide a method for producing the derivative. SOLUTION: The 4-hydroxytetrahydropyran derivative represented by general formula (6) is produced by reacting 5-halotetrahydropyran-4-ones with a phenyl Grignard reagent. (In the formula, R<SP>1</SP>, R<SP>2</SP>. R<SP>3</SP>, R<SP>4</SP>and R<SP>5</SP>are each independently hydrogen, 1-4C alkoxy or fluorine; R<SP>6</SP>is 3-10C cycloalkyl which may be substituted; and Y<SP>2</SP>is halogen). COPYRIGHT: (C)2011,JPO&INPIT
|