发明名称 |
TRANSGENIC NON-HUMAN ANIMAL AND USES THEREOF |
摘要 |
<p>The present invention relates generally to transgene constructs, transgenic non-human animals comprising transgene constructs, methods of making and methods of using the transgenic non-human animals comprising transgene constructs. An embodiment of the invention relates to methods of assaying the activation of GPCR ligands non-invasively in whole animals, tissue slices, or in native cells using a transgenic model containing a bioluminescent transgene reporter system that is responsive to pathway modulation following ligand binding of GPCR receptors.</p> |
申请公布号 |
CA2784429(A1) |
申请公布日期 |
2011.07.14 |
申请号 |
CA20102784429 |
申请日期 |
2010.12.17 |
申请人 |
SANOFI |
发明人 |
DRESSLER, HOLLY;ECONOMIDES, KYRIAKOS D.;PANG, ZHEN;POLITES, HARRY GREGORY |
分类号 |
C12N9/02;A01K67/027;C12N15/85;C12Q1/66;G01N33/50 |
主分类号 |
C12N9/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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