发明名称 |
FORMULATIONS OF DAPTOMYCIN |
摘要 |
Long term storage stable daptomycin-containing compositions are disclosed. The compositions include daptomycin or a pharmaceutically acceptable salt thereof at a concentration of less than or equal to about 25 mg/mL, a buffer having an acidic functional group and have a pH of from about 6.0 to about 7. The formulations are surprisingly free of degradation products such as the hydrolysis product of daptomycin and theβ-isomer of daptomycin after storage periods of at least about 18 months.
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申请公布号 |
US2011172167(A1) |
申请公布日期 |
2011.07.14 |
申请号 |
US20100884653 |
申请日期 |
2010.09.17 |
申请人 |
EAGLE PHARMACEUTICALS, INC. |
发明人 |
PALEPU NAGESH R.;TEJA BULUSU BHANU |
分类号 |
A61K38/12 |
主分类号 |
A61K38/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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