发明名称 |
Hydrophilic filtration during manufacture of vaccine adjuvants |
摘要 |
An improved method for the manufacture of an oil-in-water emulsion involves three procedures: (i) preparation of a preliminary emulsion; (ii) microfluidization of the preliminary emulsion to reduce its droplet size; and (iii) filtration of the microfluidized emulsion through a hydrophilic membrane. The emulsions are useful as vaccine adjuvants.
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申请公布号 |
EP2343052(A1) |
申请公布日期 |
2011.07.13 |
申请号 |
EP20100252044 |
申请日期 |
2010.12.03 |
申请人 |
NOVARTIS AG |
发明人 |
KRAUS, GOTTFRIED;ESKES, ROBERT |
分类号 |
A61K9/107;A61K39/12;A61K39/39 |
主分类号 |
A61K9/107 |
代理机构 |
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地址 |
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