| 摘要 |
<p>The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or N-oxide thereof:
wherein:
€¢ L represents a direct bond or a -S(O) 2 - group,
€¢ n is an integer having a value from 0 to 2,
€¢ R1 represents a pyridyl group or an imidazo[1,2-a]pyridinyl group, wherein the pyridyl group is substituted with one or more substituents selected from halogen atoms, a hydroxy group, a C 1-4 alkyl group and a C 1-4 alkoxy group, or
€¢ R 1 represents a group of formula:
wherein:
o R a and R b independently represent a hydrogen atom, halogen atom or a linear or branched C 1-4 alkyl group,
o R c represents a hydroxy group, a linear or branched C 1-4 alkyl group or C 1-4 alkoxy group wherein the alkyl and the alkoxy groups independently are optionally substituted with one or more substituents selected from hydroxy group, cyano group and-NR'R" groups and wherein
– R' represents a hydrogen atom or a linear or branched C 1-4 alkyl group,
– R" represents a hydrogen atom or a linear or branched C 1-4 alkyl group optionally substituted with a hydroxycarbonyl group; or
– R' and R" together with the nitrogen atom to which they are attached form a 4 to 6 membered, saturated heterocyclic ring optionally substituted with a hydroxycarbonyl group.
€¢ R 2 represents a pyridyl group, a C 3-6 cycloalkyl group or a phenyl group which is optionally substituted with one or more substituents selected from halogen atoms, cyano group, and C 1-4 alkoxy group; and
€¢ R 3 represents a C 3-6 cycloalkyl group, a C 3-6 cycloalkyl-C 1-2 alkyl group or a linear or branched C 2-4 alkyl group optionally substituted with one or more substituents selected from halogen atoms and C 1-2 alkoxy group.</p> |
