发明名称 |
BONE DELIVERY CONJUGATES AND METHOD OF USING SAME TO TARGET PROTEINS TO BONE |
摘要 |
A bone delivery conjugate having a structure selected from the group consisting of :A) X-D n -Y-protein-Z; and B) Z-protein-Y- D n -X, wherein X is absent or is an amino acid sequence of at least one amino acid; Y is absent or is an amino acid sequence of at least one amino acid; Z is absent or is an amino acid sequence of at least one amino acid; and D n is a poly aspartate wherein n = 10 to 16. Compositions comprising same and uses thereof. |
申请公布号 |
PT1759001(E) |
申请公布日期 |
2011.07.12 |
申请号 |
PT20050739065T |
申请日期 |
2005.04.21 |
申请人 |
ENOBIA PHARMA INC. |
发明人 |
PHILIPPE CRINE;GUY BOILEAU;ISABELLE LEMIRE;THOMAS P. LOISEL |
分类号 |
C12N15/62;A61K38/46;A61K38/48;A61K47/48;A61P19/08;C12N9/14;C12N9/16;C12N9/50;C12N9/64;C12N15/55;C12N15/57;G01N33/68 |
主分类号 |
C12N15/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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