发明名称 BORON COMPOUNDS EFFECTIVE IN BORON NEUTRON CAPTURE THERAPY
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to a compound of formula (I) where one of R1 and R2 represents -NH-X-Y-Z, and another represents -OH; where X represents -(CH2)m- where m is equal to 0, 1, 2, 3 or 4; Y represents carborane where at least one boron atom represents 10B; and Z represents H; and its pharmaceutically acceptable salts, solvates and stereoisomers. Also, the pharmaceutical compositions, application of the compound of formula (I) and a method of producing the compound of formula (I) are offered. ^ EFFECT: production of the compounds effective for boron neutron capture therapy. ^ 15 cl, 6 ex, 3 tbl
申请公布号 RU2423368(C2) 申请公布日期 2011.07.10
申请号 RU20080110472 申请日期 2006.08.17
申请人 KHAMMERKAP AB 发明人 OL'SSON LARS-INGE;ARZEL' EHRVAN;EHEHK ARNE
分类号 A61K31/69;C07F5/02 主分类号 A61K31/69
代理机构 代理人
主权项
地址