发明名称 |
FGF RECEPTOR-ACTIVATING N-ACYL OCTASACCHARIDES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF |
摘要 |
The invention relates to FGF receptor-activating N-acyl octasaccharides having Formula (I), wherein: R1 is an O-alkyl group optionally replaced by one or more aryl or cycloalkyl groups, R2 is an OSO3- or hydroxyl group, R3 is an alkyl, cycloalkyl, or alky-cycloalkyl group, R4 is a disaccharide having Formula (II), R6 is a disaccharide having Formula (III), and R8 is a disaccharide having Formula (IV), where R5, R7, and R9 have OSO3 or hydroxyl groups. The invention further relates to the preparation of said octasaccharides and to the therapeutic use thereof. |
申请公布号 |
WO2011018588(A3) |
申请公布日期 |
2011.07.07 |
申请号 |
WO2010FR51703 |
申请日期 |
2010.08.12 |
申请人 |
SANOFI-AVENTIS;DRIGUEZ, PIERRE ALEXANDRE;DUCHAUSSOY, PHILIPPE;FONS, PIERRE;HERBERT, CORENTIN;LASSALLE, GILBERT |
发明人 |
DRIGUEZ, PIERRE ALEXANDRE;DUCHAUSSOY, PHILIPPE;FONS, PIERRE;HERBERT, CORENTIN;LASSALLE, GILBERT |
分类号 |
C08B37/00;A61K31/737;C07H13/04;C07H13/12;C07H15/203 |
主分类号 |
C08B37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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