发明名称 |
ANTI-IGA1 ANTIBODY |
摘要 |
Provided is a monoclonal antibody, effective in diagnosing IgA nephropathy, that specifically recognizes and bonds to the hinge region of a polypeptide coded for by the immunoglobulin A1 heavy chain gene, which contains a serine/threonine-linked sugar chain with no galactose bound thereto. Also provided are a fragment of said antibody, a diagnostic agent using the provided antibody or antibody fragment, and a therapeutic agent containing the provided antibody or antibody fragment as an active ingredient. |
申请公布号 |
CA2789196(A1) |
申请公布日期 |
2011.07.07 |
申请号 |
CA20102789196 |
申请日期 |
2010.12.28 |
申请人 |
KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
KANEKO, ETSUJI;SASAKI, YUKA;MORI, KATSUHIRO;KANDA, YUTAKA;SATOH, MITSUO |
分类号 |
C12N15/09;A61K39/395;A61P13/12;A61P37/02;C07K16/42;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/02;C12P21/08;G01N33/53 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|