发明名称 ANTI-IGA1 ANTIBODY
摘要 Provided is a monoclonal antibody, effective in diagnosing IgA nephropathy, that specifically recognizes and bonds to the hinge region of a polypeptide coded for by the immunoglobulin A1 heavy chain gene, which contains a serine/threonine-linked sugar chain with no galactose bound thereto. Also provided are a fragment of said antibody, a diagnostic agent using the provided antibody or antibody fragment, and a therapeutic agent containing the provided antibody or antibody fragment as an active ingredient.
申请公布号 CA2789196(A1) 申请公布日期 2011.07.07
申请号 CA20102789196 申请日期 2010.12.28
申请人 KYOWA HAKKO KIRIN CO., LTD. 发明人 KANEKO, ETSUJI;SASAKI, YUKA;MORI, KATSUHIRO;KANDA, YUTAKA;SATOH, MITSUO
分类号 C12N15/09;A61K39/395;A61P13/12;A61P37/02;C07K16/42;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/02;C12P21/08;G01N33/53 主分类号 C12N15/09
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