发明名称 Detection of mutations in a gene associated with resistance to viral infection, OASI
摘要 A method for detecting a mutation related to the gene encoding OAS 1. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide 5 encoded by the mutated gene, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human OAS 1, including antisense oligonucleotides, methods, and compositions specific for human OAS 1, are also provided.
申请公布号 AU2011202885(A1) 申请公布日期 2011.07.07
申请号 AU20110202885 申请日期 2011.06.16
申请人 ILLUMIGEN BIOSCIENCES, INC. 发明人 IADONATO, SHAWN P.;MAGNESS, CHARLES L.;ROSENBURG, GARY;SCHERER, CHRISTINA A.;GUILLAUDEUX, THIERRY
分类号 C12N9/12;C12Q1/68;C12Q1/70 主分类号 C12N9/12
代理机构 代理人
主权项
地址