发明名称 |
Detection of mutations in a gene associated with resistance to viral infection, OASI |
摘要 |
A method for detecting a mutation related to the gene encoding OAS 1. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide 5 encoded by the mutated gene, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human OAS 1, including antisense oligonucleotides, methods, and compositions specific for human OAS 1, are also provided. |
申请公布号 |
AU2011202885(A1) |
申请公布日期 |
2011.07.07 |
申请号 |
AU20110202885 |
申请日期 |
2011.06.16 |
申请人 |
ILLUMIGEN BIOSCIENCES, INC. |
发明人 |
IADONATO, SHAWN P.;MAGNESS, CHARLES L.;ROSENBURG, GARY;SCHERER, CHRISTINA A.;GUILLAUDEUX, THIERRY |
分类号 |
C12N9/12;C12Q1/68;C12Q1/70 |
主分类号 |
C12N9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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