发明名称 HOMING IN MESENCHYMAL STEM CELLS
摘要 The present invention relates to expression of CXCR4 in mesenchymal stem cells (MSCs) and homing of MSCs to sites of injury. In particular, the invention provides expanded cultures of MSCs which maintain cell surface expression of CXCR4. The MSCs are capable of homing to sites of injury and are suitable for treatment of ischemic disorders, including cardiac disorders, bone and cartilage disorders, liver disorders, inflammatory disorders, and stroke.
申请公布号 US2011165128(A1) 申请公布日期 2011.07.07
申请号 US20090921396 申请日期 2009.03.06
申请人 COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 发明人 DORONIN SERGEY V.;POTAPOVA IRINA A.;COHEN IRA S.;ROSEN MICHAEL R.;ROBINSON RICHARD B.;BRINK PETER R.
分类号 A61K35/12;A61P9/00;A61P9/10;C12N5/0775 主分类号 A61K35/12
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