发明名称 |
MHC Class I Peptide Epitopes from the Human 5T4 Tumor-Associated Antigen |
摘要 |
There is provided an MHC class I peptide epitope from 5T4 antigen. In particular, there is provided a peptide epitope of 5T4 which comprises one of the following: (i) the amino acid sequence shown as SEQ ID NO: 2; (ii) the minimal epitope from the amino acid sequence shown as SEQ ID NO: 3; (iii) the minimal epitope from the amino acid sequence shown as SEQ ID NO: 4; (iv) the minimal epitope from the amino acid sequence shown as SEQ ID NO: 5; (v) the minimal epitope from the amino acid sequence shown as SEQ ID NO: 6; (vi) the minimal epitope from the amino acid sequence shown as SEQ ID NO: 7. There is also provided a vaccine comprising such a peptide (or precursor thereof) and its use to treat and/or prevent a disease, in particular a cancerous disease.
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申请公布号 |
US2011165668(A1) |
申请公布日期 |
2011.07.07 |
申请号 |
US20110983744 |
申请日期 |
2011.01.03 |
申请人 |
OXFORD BIOMEDICA (UK) LIMITED |
发明人 |
CARROLL MILES;KINGSMAN SUSAN;REDCHENKO IRINA |
分类号 |
C12N15/63;A61K39/00;C07K1/06;C07K14/47;C12N15/12 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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