发明名称 BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS
摘要 The present invention provides Gyrase B and/or Topoisomerase IV par E inhibitors, which can be used as antibacterial agents. Compounds disclosed herein can be used for treating or preventing conditions caused by or contributed by gram positive, gram negative and anaerobic bacteria, more particularly against, for example, Staphylococci, Streptococci, Enterococci, Haemophilus, Pseudomonas spp., Acenetobacter spp., Moraxalla spp., Chlamydia spp., Mycoplasma spp., Legionella spp., Ktycobacterium spp., Helicobacter, Clostridium spp., Bacteroides spp., Corynebacterium, Bacillus spp., Enterobactericeae,’ (E. coli, Klebsiella spp., Proteus spp., etc.) or any combination thereof. Also provided, are processes for preparing compounds disclosed herein, pharmaceutical compositions containing compounds disclosed herein, and methods of treating bacterial infections. (Formula)
申请公布号 US2011166088(A1) 申请公布日期 2011.07.07
申请号 US200913000561 申请日期 2009.06.25
申请人 RANBAXY LABORATORIES LIMITED 发明人 SATTIGERI JITENDRA A.;KUMAR NARESH;YADAV AJAY;SHARMA LALIMA;CLIFFE IAN A.;VARUGHESE SHIBU B.;SHABBIR SHAIKH RIZWAN;RAJ V. SAMUEL;UPADHYAY DILIP J.;BHATNAGER PRADIP K.
分类号 A61K31/7068;A61K31/4439;A61K31/444;A61K31/496;A61K31/506;A61K31/513;A61K31/5355;A61P31/04;C07D413/14;C07D417/14;C07H17/02 主分类号 A61K31/7068
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