发明名称 |
NEURAMINIC ACID DERIVATIVE, SIALIDASE ACTIVITY INHIBITOR AND ANTIINFLUENZA DRUG |
摘要 |
Provided are a neuraminic acid derivative, which selectively inhibits virus sialidase activity but little inhibits human sialidase activity, a sialidase activity inhibitor, and an antiinfluenza drug. The aforesaid neuraminic acid derivative is characterized by comprising a compound represented by chemical formula (1), a pharmaceutically acceptable salt thereof, a hydrate of the same, a solvate of the same or a prodrug of the same. In chemical formula (1), R1 and R2 represent hydrogen, an optionally branched C1-8 alkyl group or an optionally branched C1-8 cycloalkyl group; and R3 represents hydrogen or fluorine. |
申请公布号 |
WO2011081083(A1) |
申请公布日期 |
2011.07.07 |
申请号 |
WO2010JP73284 |
申请日期 |
2010.12.24 |
申请人 |
GIFU UNIVERSITY;CHUBU UNIVERSITY;KISO, MAKOTO;ISHIDA, HIDEHARU;SADAGOPAN, MAGESH;SUZUKI, YASUO;MIYAGI, TAEKO |
发明人 |
KISO, MAKOTO;ISHIDA, HIDEHARU;SADAGOPAN, MAGESH;SUZUKI, YASUO;MIYAGI, TAEKO |
分类号 |
C07D309/28;A61K31/351;A61P31/16;A61P43/00 |
主分类号 |
C07D309/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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