发明名称 NEURAMINIC ACID DERIVATIVE, SIALIDASE ACTIVITY INHIBITOR AND ANTIINFLUENZA DRUG
摘要 Provided are a neuraminic acid derivative, which selectively inhibits virus sialidase activity but little inhibits human sialidase activity, a sialidase activity inhibitor, and an antiinfluenza drug. The aforesaid neuraminic acid derivative is characterized by comprising a compound represented by chemical formula (1), a pharmaceutically acceptable salt thereof, a hydrate of the same, a solvate of the same or a prodrug of the same. In chemical formula (1), R1 and R2 represent hydrogen, an optionally branched C1-8 alkyl group or an optionally branched C1-8 cycloalkyl group; and R3 represents hydrogen or fluorine.
申请公布号 WO2011081083(A1) 申请公布日期 2011.07.07
申请号 WO2010JP73284 申请日期 2010.12.24
申请人 GIFU UNIVERSITY;CHUBU UNIVERSITY;KISO, MAKOTO;ISHIDA, HIDEHARU;SADAGOPAN, MAGESH;SUZUKI, YASUO;MIYAGI, TAEKO 发明人 KISO, MAKOTO;ISHIDA, HIDEHARU;SADAGOPAN, MAGESH;SUZUKI, YASUO;MIYAGI, TAEKO
分类号 C07D309/28;A61K31/351;A61P31/16;A61P43/00 主分类号 C07D309/28
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