发明名称 |
MODIFIED BACTERIAL STRAIN AND USE THEREOF |
摘要 |
The present invention relates to a mutant of Salmonella gallinarum that is defective in the CobS and CbiA (SGCobSCbiA) genes, which are associated with the production of cobalamin by the bacterium in anaerobic conditions, for use as vaccines. The present invention also relates to the use of said mutant Salmonella gallinarum strain for inducing protection in birds against infection by the homologous natural strain and Salmonella enteritidis strain by means of a vaccine. |
申请公布号 |
WO2011079361(A1) |
申请公布日期 |
2011.07.07 |
申请号 |
WO2010BR00431 |
申请日期 |
2010.12.22 |
申请人 |
UNIVERSIDADE ESTADUAL PAULISTA "JULIO DE MESQUITAFILHO" - UNESP;FUNDACAO DE AMPARO A PESQUISA DO ESTADO DE SAO PAULO;BERCHIERI, ANGELO JR. |
发明人 |
BERCHIERI, ANGELO JR. |
分类号 |
C12N15/66;A61K39/112;C12Q1/68;C12R1/42 |
主分类号 |
C12N15/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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