摘要 |
Phenyl pyrimidone compounds, pharmaceutical compositions, preparation methods and uses thereof. In particular to phenyl pyrimidone compounds of formula I, pharmaceutical acceptable salts or solvates, pharmaceutical compositions and preparation methods thereof. The compounds of formula I are effective for inhibiting V form phosphodiesterase enzyme (PDE5), and could be applied to treating various vein dysfunctional diseases such as male erectile dysfunction, pulmonary hypertension et al. |
申请人 |
TOPHARMAN SHANGHAI CO., LTD.;SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES;TOPHARMAN SHANDONG CO., LTD. |
发明人 |
LIU, ZHENG;LI, JIANFENG;YANG, XIAOJUN;WANG, ZHEN;ZHANG, JINFENG;ZHU, YI;TIAN, GUANGHUI;JIN, QING;SHEN, JINGKANG;ZHU, WEILIANG;JIANG, HUALIANG;SHEN, JINGSHAN |