| 发明名称 |
Gamma Secretase Modulators |
| 摘要 |
The present invention provides compounds that are gamma secretase modulators and are therefore useful for the treatment of diseases treatable by modulation of gamma secretase such as Alzheimer's disease. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
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| 申请公布号 |
US2011166132(A1) |
申请公布日期 |
2011.07.07 |
| 申请号 |
US20080746902 |
申请日期 |
2008.12.12 |
| 申请人 |
AMGEN INC. |
发明人 |
HITCHCOCK STEPHEN A.;CHEN JIAN J.;NCUBE MQHELE VELLAH;NIXEY THOMAS;AMEGADZIE ALBERT;KUNZ ROXANNE;QIAN WENYAN;CHEN NING;TEGLEY CHRISTOPHER M.;DE MORIN FRENEL F.;YUAN CHESTER CHENGUANG;LIU QINGYIAN;ZHU JIAWANG;PETERKIN TANYA A.N.;ADAMS JEFFREY A.;HU ESSA;CHAVEZ, JR. FRANK |
| 分类号 |
A61K31/538;A61K31/4164;A61K31/4178;A61K31/4418;A61K31/4433;A61K31/4439;A61K31/444;A61K31/4545;A61K31/4709;A61K31/4725;A61K31/496;A61K31/5377;A61P25/28;C07D213/56;C07D233/61;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D413/12;C07D413/14 |
主分类号 |
A61K31/538 |
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