发明名称 GANGLIOSIDES WITH A MODIFIED ACYL FUNCTION
摘要 The invention relates to a ganglioside mixture, containing of consisting of gangliosides, of the following general formula: (sugar)-OCH~2-CH(-NH-CO-R1~)-CH(OH)-CH=CH-R2~, wherein (sugar) represents a sugar radical, the group -CO-R1~ represents an acyl-fatty acid which is bonded to the radical of the molecule in the form of an amide, Rl~ represents a straight, saturated alkyl radical having at least 10 C-atoms and R2~ represents a straight, saturated alkyl radical having at least 10 C-atoms or a straight alkenyl radical having at least 10 C-atoms and one, two or three double bond(s). Said mixture is characterised in that at least 10 wt. % of the gangliosides of the general formula I are of the group -CO-R1~ and the acyl-fatty acids are a C20:0 fatty acid. Said mixtures exhibit an improved biological activity.
申请公布号 CA2489456(C) 申请公布日期 2011.07.05
申请号 CA20032489456 申请日期 2003.05.27
申请人 N.V. NUTRICIA 发明人 BEERMANN, CHRISTOPHER;BODE, LARS;BOEHM, GUNTHER
分类号 C07H15/10;A23L1/29;A23L1/30;A61K31/7004;A61K31/7028;A61K31/7032;A61P3/02 主分类号 C07H15/10
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