发明名称 Imidazole derivatives
摘要 The present invention relates to process for the preparation of an imidazole derivative of formula I, wherein R1, R2, R3 and R4 are described hereinabove. These compounds can be used in the treatment or prevention of mGluR5 receptor mediated disorders. These compounds are useful, inter alia, in the treatment or prevention of acute and/or chronic neurological disorders such as psychosis, epilepsy, schizophrenia, Alzheimer' disease, cognitive disorders and memory deficits, as well as chronic and acute pain.
申请公布号 US7973165(B2) 申请公布日期 2011.07.05
申请号 US20070955421 申请日期 2007.12.13
申请人 HOFFMANN-LA ROCHE INC. 发明人 BUETTELMANN BERND;CECCARELLI SIMONA MARIA;JAESCHKE GEORG;KOLCZEWSKI SABINE;PORTER RICHARD HUGH PHILIP;VIEIRA ERIC
分类号 C07D401/06;A61P25/28;C07D401/14 主分类号 C07D401/06
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