摘要 |
PROBLEM TO BE SOLVED: To provide a method for treating disease states associated with angiogenesis and/or exacerbated vascular permeability. SOLUTION: A quinazoline derivative is represented by formula (I) (wherein ring C is a 5-6-membered heterocyclic moiety; Z is -O-, -NH-, -S- or -CH<SB>2</SB>-; and R<SP>1</SP>is any substituent of H, 1-4C alkyl 1-4C alkoxymethyl and the like). COPYRIGHT: (C)2011,JPO&INPIT |