发明名称 Hemifumarate salt of 1- [4- [1- ( 4 -cyclohexyl-3 -trifluoromethyl-benzyloxyimino ) -ethyl] -2 -ethyl-benzyl] -a zetidine-3-carboxylic acid
摘要 This invention relates to a hemifumarate salt of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic acid (Compound I), to pharmaceutical compositions comprising this salt, to processes for forming this salt and to its use in medical treatment. In addition, the present invention also relates to new polymorphic forms of the hemifumarate salt form of Compound I, as well as to pharmaceutical compositions comprising these polymorphic forms, to processes for obtaining them, and their use in medical treatment.
申请公布号 AU2009335924(A1) 申请公布日期 2011.06.30
申请号 AU20090335924 申请日期 2009.12.16
申请人 NOVARTIS AG 发明人 CISZEWSKI, LECH;DE LA CRUZ, MARILYN;KARPINSKI, PIOTR H.;MUTZ, MICHAEL;RIEGERT, CHRISTIAN;VOGEL, CASPAR;SCHNEEBERGER, RICARDO
分类号 C07D205/04;A61K31/397;A61P35/00;A61P37/00 主分类号 C07D205/04
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