发明名称 N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF
摘要 The present invention relates to a novel N-phenyl-2-pyrimidine-amine derivative represented by the above formula (1) and its salt showing a superior effect on cancer in warm-blooded animals, such as lung cancer, gastric cancer, colon cancer, pancreatic cancer, hepatoma, prostatic cancer, breast cancer, chronic or acute leukemia, hematologic malignancy, encephalophyma, bladder cancer, rectal cancer, cervical cancer, lymphoma, etc. The present invention also relates to a process for preparing the compound, and to a pharmaceutical composition for the treatment of the above various diseases, which comprises an effective amount of the compound as an active ingredient together with pharmaceutically acceptable inert carriers.wherein R-Rsuch as given in the specification.
申请公布号 EA015103(B1) 申请公布日期 2011.06.30
申请号 EA20080000516 申请日期 2005.09.07
申请人 IL-YANG PHARM. CO., LTD. 发明人 KIM DONG-YEON;CHO DAE-JIN;LEE GONG-YEAL;KIM HONG-YOUB;WOO SEOK-HUN;KIM YONG-SEOK;LEE SUN-AHE;HAN BYOUNG-CHEOL
分类号 C07D239/02;A61K31/425;A61K31/44;A61K31/4965;A61K31/505;A61P35/00;C07D239/28;C07D401/02;C07D417/00 主分类号 C07D239/02
代理机构 代理人
主权项
地址