发明名称 ANTICANCER COMBINATIONS OF ARTEMISININ-BASED DRUGS AND OTHER CHEMOTHERAPEUTIC AGENTS
摘要 The present invention relates to combinations between artemisinin-based potent anti-malarial agents, selected from the group consisting of ART, DHA and ARM, and a further chemotherapeutic drug selected from the group consisting of a camptothecin derivative, or a PARP-1 inhibitor, or an intercalating DNA agent, or an alkylating agent. Such combinations, showed medium to strong synergism in various models of cancer, in particular in NSCL.
申请公布号 CA2780591(A1) 申请公布日期 2011.06.30
申请号 CA20102780591 申请日期 2010.12.06
申请人 SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. 发明人 PISANO, CLAUDIO;VESCI, LOREDANA
分类号 A61K31/24;A61K31/335;A61K31/4745;A61K31/704;A61P35/00 主分类号 A61K31/24
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