CELL-BASED SCREENING ASSAY TO IDENTIFY MOLECULES THAT STIMULATE IFN-ALPHA/BETA TARGET GENES

摘要

A method using cells transformed with a construct containing a reporter gene operatively-linked to an interferon stimulated response element for identifying an agent, such as a chemical compound, peptide or polypeptide, which exhibits an interferon-like activity on the interferon stimulated response element (ISRE) and modulates genes activated by activation of the ISRE.