The present invention provides novel radio iodinated tropanes incorporating triazole or isoxazole rings. Also provided are methods of preparation of said tropanes from functionalised tropane precursors, using click cycloaddition chemistry, as well as radiopharmaceutical compositions comprising such radio iodinated tropanes. The invention also provides in vivo imaging methods using the radio iodinated tropanes.
申请公布号
WO2011076778(A1)
申请公布日期
2011.06.30
申请号
WO2010EP70352
申请日期
2010.12.21
申请人
GE HEALTHCARE LIMITED;AVORY, MICHELLE;WADSWORTH, HARRY;NAIRNE, JAMES DOMETT
发明人
AVORY, MICHELLE;WADSWORTH, HARRY;NAIRNE, JAMES DOMETT