发明名称 BIOMARKERS OF MINERALOCORTICOID RECEPTOR ACTIVATION
摘要 The present invention relates to the use of Neutrophil Gelatinase-Associated Lipocalin (NGAL) and/or SERPINA3 as biomarkers of the Mineralocorticoid Receptor (MR) activation in a patient. More particularly, the present invention relates to a method for predicting the responsiveness of a patient to a treatment with a MR antagonist or an aldosterone synthase inhibitor, said method comprising determining in a biological sample obtained from said patient the expression level of the NGAL gene and/or of the SERPINA3 gene.
申请公布号 IL212231(D0) 申请公布日期 2011.06.30
申请号 IL20110212231 申请日期 2011.04.10
申请人 INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) 发明人
分类号 C12Q 主分类号 C12Q
代理机构 代理人
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