发明名称 |
BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE |
摘要 |
The present invention relates to a benzylphenyl glucopyranoside derivative having an excellent inhibitory effect on human SGLT1 and/or SGLT2 activity. There is provided a compound or a pharmacologically acceptable salt thereof represented by the following general formula (I):
wherein
R 1 represents a hydrogen atom, an amino group, a hydroxy C 1 -C 6 alkyl group, etc.; R 2 represents a hydrogen atom, etc.; R 3 represents a C 1 -C 6 alkyl group, a hydroxy C 1 -C 6 alkyl group, etc.; R 4 represents a hydrogen atom, a C 2 -C 7 acyl group, etc.; R 5 , R 6 , R 7 , and R 8 are the same or different and each represents a hydrogen atom or a C 1 -C 6 alkyl group, provided that R 5 , R 6 , R 7 and R 8 are not hydrogen atoms at the same time; n is 0 to 4; and X is CH or N. |
申请公布号 |
EP2048150(A4) |
申请公布日期 |
2011.06.29 |
申请号 |
EP20070791905 |
申请日期 |
2007.08.03 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
HONDA, TAKESHI;OGUCHI, MINORU;YOSHIDA, MASAO;OKUYAMA, RYO;OGATA, TSUNEAKI;ABE, MANABU;UEDA, KENJIRO;OHSUMI, JUN;IZUMI, MASANORI |
分类号 |
C07H15/203;A61K31/7034;A61K31/7036;A61P1/16;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P7/10;A61P9/04;A61P9/10;A61P9/12;A61P13/12;A61P19/06;A61P25/02;A61P27/02;A61P27/12;A61P31/00;A61P43/00;C07H17/02 |
主分类号 |
C07H15/203 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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