发明名称 BENZOTHIAZOLE DERIVATIVES
摘要 The present invention relates to compounds of the general formula (I) and to their pharmaceutically acceptable salts for the treatment of diseases related to the adenosine A2 receptor, novel compounds of formula I-A per se,their manufacture, medicaments based on a compound in accordance with the invention and their production as well as the use of compounds of compounds of formula I in the control or prevention of illnesses based on the modulation of the adenosine system, such as Alzheimer's disease, Parkinson's disease, neuroprotection, schizophrenia, anxiety, pain, respiration deficits, depression, asthma, allergic responses hypoxia, ischaemia, seizure and substance abuse. Furthermore, compounds of the present invention may be useful as sedatives, muscle relaxants, antipsychotics, antiepileptics, anticonvulsants and cardiaprotective agents.
申请公布号 CA2413086(C) 申请公布日期 2011.06.28
申请号 CA20012413086 申请日期 2001.06.08
申请人 F. HOFFMANN-LA ROCHE AG 发明人 ALANINE, ALEXANDER;FLOHR, ALEXANDER;MILLER, AUBRY KERN;NORCROSS, ROGER DAVID;RIEMER, CLAUS
分类号 C07D417/14;A61K31/422;A61K31/423;A61K31/427;A61K31/428;A61K31/4439;A61K31/444;A61K31/4545;A61K31/455;A61K31/4725;A61K31/496;A61K31/5375;A61K31/5377;A61K31/541;A61K31/551;A61K31/5513;A61P11/06;A61P21/02;A61P25/04;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/26;A61P25/28;C07D277/82;C07D413/04;C07D417/04;C07D417/12 主分类号 C07D417/14
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