发明名称 |
PYRIDAZINONE DERIVATIVES AS THYROID HORMONE RECEPTOR AGONISTS |
摘要 |
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the sub-stituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as obesity, hyperlipidemia, hypercholes-terolemia and diabetes and other related disorders and diseases, and may be useful for other diseases such as NASH, atherosclerosis, car-diovascular diseases, hypothyroidism, thyroid cancer and other disor-ders and diseases related thereto. |
申请公布号 |
CA2614529(C) |
申请公布日期 |
2011.06.28 |
申请号 |
CA20062614529 |
申请日期 |
2006.07.11 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
HAYNES, NANCY-ELLEN;KERTESZ, DENIS JOHN;PIETRANICO-COLE, SHERRIE LYNN;QIAN, YIMIN;SCOTT, NATHAN ROBERT;SO, SUNG-SAU;THAKKAR, KSHITIJ CHHABILBHAI;TILLEY, JEFFERSON WRIGHT |
分类号 |
C07D237/14;A61K31/501;A61P5/16;C07D237/16;C07D237/18;C07D403/10;C07D403/12 |
主分类号 |
C07D237/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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