METHOD OF PRODUCING SUCCINIC ACID WITH USING Yarrowia YEAST

摘要

FIELD: medicine. ^ SUBSTANCE: invention refers to a method of producing succinic acid with using a Yarrowia lipolytica yeast strain, Russian National Collection of Industrial Microorganisms No. Y-3314. Said yeast is modified in such a manner that they have lowered succinate dehydrogenase activity. The method involves a stage of yeast strain incubation in a nutrient medium containing glycerine, and recovery of succinic acid from a culture fluid. ^ EFFECT: use of the Yarrowia lipolytica strain, Russian National Collection of Industrial Microorganisms No Y-3314 has ensured substantially increased yield of succinic acid in this method. ^ 2 cl, 2 dwg, 5 tbl, 5 ex