TRANSCRIPT VARIANTS OF VNN1 AND SLC39A14

摘要

The present inventors here present a novel strategy for identification of RNA transcript variants and demonstrate that these can be correlated to disease states in mammals such as cancer. In particular, the transcript variants show prevalence and specificity to cancer, and thus also show clinical applicability in e.g. cancer diagnostics and prognostics, treatment and therapeutics. The present inventors have identified RNA transcript variants of SLC39A14 that can be used as biomarkers. The RNA transcript variant may also be used as biomarkers for diagnosing, prognosing, monitoring, and or treatment selection for a cancer or the precursor to a cancer.