发明名称 METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS
摘要 A lipid particle can include a plurality of cationic lipids, such as a first cationic lipid and a second cationic lipid. The first cationic lipid can be selected on the basis of a first property and the second cationic can be selected on the basis of a second property. The first and second properties are complementary. The attributes of the lipid particle can reflect the selected properties of the cationic lipids, and the complementary nature of those properties.
申请公布号 CA2784568(A1) 申请公布日期 2011.06.23
申请号 CA20102784568 申请日期 2010.12.17
申请人 ALNYLAM PHARMACEUTICALS, INC.;THE UNIVERSITY OF BRITISH COLUMBIA 发明人 MAIER, MARTIN A.;JAYARAMAN, MUTHUSAMY;RAJEEV, KALLANTHOTTATHIL G.;AKINC, AKIN;MANOHARAN, MUTHIAH;HOPE, MICHAEL J.;MADDEN, THOMAS D.;CULLIS, PIETER
分类号 B01J13/02;A61K9/127;A61K31/7088;C12N15/113;C12N15/87;C12N15/88 主分类号 B01J13/02
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