HETEROAROMATIC ARYL TRIAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS
摘要
<p>This invention is directed to compounds (Formula 1), which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula (I). The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I). The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula (I). The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I).</p>
申请公布号
WO2011072697(A1)
申请公布日期
2011.06.23
申请号
WO2010DK50344
申请日期
2010.12.15
申请人
H. LUNDBECK A/S;PUESCHL, ASK;NIELSEN, JACOB;KEHLER, JAN;KILBURN, JOHN, PAUL;MARIGO, MAURO;LANGGAARD, MORTEN